Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091483 | 0.84 | FFAR1 (0.47) | FFAR1RAB9A | |
| SCHEMBL11099780 | 0.78 | HDAC1 (0.43) | CYP1A2MEN1KMT2ALMNA | |
| SCHEMBL11074467 | 0.76 | LMNA (0.46) | CYP1A2FFAR1LMNARAB9A | |
| SCHEMBL346302 | 0.74 | FFAR1 (0.65) | CYP1A2FFAR1LMNARAB9A | |
| SCHEMBL29824310 | 0.74 | PTGS1 (0.67) | CYP1A2CTBP2MEN1KMT2ALMNA | |
| SCHEMBL229067 | 0.74 | PTGS1 (0.67) | CYP1A2CTBP2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8693464 | 0.73 | CTBP2 (0.65) | CYP1A2CTBP2MEN1KMT2ALMNA | |
| SCHEMBL8218805 | 0.73 | CTBP2 (0.65) | CYP1A2CTBP2MEN1KMT2ALMNA | |
| SCHEMBL8953320 | 0.72 | CYP1A2 (0.51) | CYP1A2CTBP2MEN1KMT2ASLC13A5 | |
| SCHEMBL227654 | 0.72 | CYP1A2 (0.55) | CYP1A2CTBP2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |