Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091483 | 0.79 | FFAR1 (0.47) | KDM4ETSHR | |
| SCHEMBL11099776 | 0.78 | HSD17B10 (0.51) | ALDH1A1KDM4ETDP1LMNAMEN1 | |
| SCHEMBL11074465 | 0.78 | CYP1A2 (0.48) | LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3683765 | 0.76 | FFAR4 (0.53) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL138449 | 0.75 | GAA (0.68) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL3686168 | 0.73 | SELP (0.53) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL16114691 | 0.70 | MAPT (0.49) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL2853330 | 0.70 | HDAC1 (0.58) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL12775643 | 0.69 | HTT (0.53) | HDAC1HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL21916942 | 0.69 | HDAC1 (0.54) | HDAC1HDAC6ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |