Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191864 | 0.92 | ACE (0.53) | ACEFFAR2LMNAHTTPOLB | |
| SCHEMBL10995338 | 0.89 | ACE (0.47) | ACEFFAR2KMT2ALMNA | |
| SCHEMBL10968295 | 0.85 | ACE (0.71) | ACEFFAR2KMT2ALMNAHTT | |
| SCHEMBL10944250 | 0.85 | ACE (0.53) | ACEFFAR2LMNAHTTPOLB | |
| SCHEMBL11195287 | 0.82 | ACE (0.52) | ACEFFAR2KMT2ALMNAHTT | |
| SCHEMBL11075093 | 0.81 | ACE (0.54) | ACEFFAR2LMNAHTTPOLB | |
| SCHEMBL10999357 | 0.80 | ACE (0.49) | ACEFFAR2LMNAHTTPOLB | |
| SCHEMBL11110326 | 0.77 | ACE (0.51) | ACEFFAR2KMT2ALMNAHTT | |
| SCHEMBL10999348 | 0.76 | ACE (0.47) | ACEFFAR2LMNAHTTPOLB | |
| SCHEMBL11191876 | 0.76 | ACE (0.39) | ACEFFAR2LMNAHTTTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |
| US-4496578-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-01-29 | — | — | US | disclosed |
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | disclosed |