Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078859 | 0.90 | HDAC1 (0.59) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL13314540 | 0.87 | ALDH1A1 (0.51) | RAB9ANPC1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11083276 | 0.84 | ALDH1A1 (0.57) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL10597627 | 0.80 | SMN1; SMN2 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1315526 | 0.79 | PTPN1 (0.87) | PTPN1HDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL5694517 | 0.79 | NPC1 (0.71) | PTPN1RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL11076637 | 0.79 | SMN1; SMN2 (0.55) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL4250752 | 0.78 | KCNK9 (0.81) | PTPN1HDAC2HDAC8HDAC6RAB9A | |
| SCHEMBL11083219 | 0.77 | NT5E (0.60) | RAB9ANPC1HTTALDH1A1KCNK9 | |
| SCHEMBL14715847 | 0.77 | PTPN1 (0.84) | PTPN1HDAC2HDAC8HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |