Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075282 | 0.90 | PTPN1 (0.57) | HDAC2HDAC8HDAC6KCNK9NPC1 | |
| SCHEMBL11081421 | 0.88 | NPSR1 (0.53) | HDAC8HDAC6KMT2A | |
| SCHEMBL11083219 | 0.88 | NT5E (0.60) | KCNK9NPC1RAB9ALMNAKCNK3 | |
| SCHEMBL13702145 | 0.85 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6KCNK9 | |
| SCHEMBL11079972 | 0.84 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL13314540 | 0.83 | ALDH1A1 (0.51) | HDAC1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8374911 | 0.81 | HDAC1 (0.85) | HDAC1HDAC2HDAC8HDAC6KCNK9 | |
| SCHEMBL11083276 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2LMNAKMT2AMEN1POLB | |
| SCHEMBL13701743 | 0.79 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6KCNK9 | |
| SCHEMBL14715821 | 0.78 | KCNK3 (0.85) | HDAC1HDAC2HDAC8HDAC6KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |