Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077042 | 0.90 | LMNA (0.56) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL11073535 | 0.85 | TSHR (0.60) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL11075282 | 0.84 | PTPN1 (0.57) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL11078859 | 0.81 | HDAC1 (0.59) | MEN1KMT2ALMNAKDM4EHTT | |
| SCHEMBL10597627 | 0.80 | SMN1; SMN2 (0.71) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL437231 | 0.79 | ALDH1A1 (0.87) | ALDH1A1HPGDBCAT2MEN1KMT2A | |
| SCHEMBL11076637 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL13754121 | 0.78 | HPGD (0.50) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL11266257 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HPGDBCAT2MEN1KMT2A | |
| SCHEMBL11266259 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HPGDBCAT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |