Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456813 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL17513216 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4ESMN1; SMN2GAA | |
| SCHEMBL17304775 | 0.75 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL17664707 | 0.74 | KDM4E (0.57) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL1333910 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL8409985 | 0.74 | ITGB3 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4896972 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL4896977 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL11278425 | 0.73 | HTT (0.59) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL11286791 | 0.73 | HTT (0.59) | ALDH1A1MEN1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481207-A | CALCIUM ANTAGONISTS, HYPOTENSIVES | SYNTHELABO (FR) | 1984-11-06 | — | — | US | disclosed |