Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.54 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8720171 | 0.86 | POLB (0.55) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| Hydrochloric Acid SCHEMBL8407670 | 0.85 | L3MBTL1 (0.61) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| Hydrochloric Acid SCHEMBL8409067 | 0.84 | F2 (0.51) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| SCHEMBL8886464 | 0.84 | MEN1 (0.57) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| SCHEMBL7297767 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| SCHEMBL8410661 | 0.80 | SLC6A1 (0.48) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7273455 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| Hydrochloric Acid SCHEMBL8408077 | 0.78 | F2 (0.50) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| Hydrochloric Acid SCHEMBL8410566 | 0.76 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1F2TPSAB1 | |
| SCHEMBL31367822 | 0.76 | KDM2B (0.51) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |