Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 10/20 | 0.37 |
| ▸ | CA2 | P00918 | 10/20 | 0.37 |
| ▸ | CA9 | Q16790 | 9/20 | 0.37 |
| ▸ | CA12 | O43570 | 8/20 | 0.37 |
| ▸ | CA3 | P07451 | 6/20 | 0.37 |
| ▸ | CA6 | P23280 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.37 |
| ▸ | CA5A | P35218 | 5/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075618 | 0.98 | CISD1 (0.39) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL11077293 | 0.88 | ALDH1A1 (0.42) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL11077269 | 0.86 | ALDH1A1 (0.42) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL11115185 | 0.80 | CISD1 (0.39) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL10962539 | 0.76 | CISD1 (0.66) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL11217820 | 0.76 | CISD1 (0.48) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL10963452 | 0.74 | CISD1 (0.47) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL11381881 | 0.71 | CA1 (0.51) | CISD1CA1CA2CA9CA12 | |
| Azosemide SCHEMBL231405 | 0.70 | PDE4D (0.58) | CISD1CA1CA2CA9CA12 | |
| SCHEMBL12522802 | 0.69 | PDE4D (0.55) | CISD1PDE4DPDE3AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478843-A | 5-Phenyltetrazoles and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |