Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA3 | P07451 | 6/20 | 0.42 |
| ▸ | CA6 | P23280 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 6/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA5A | P35218 | 5/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962587 | 0.86 | ALDH1A1 (0.50) | CISD1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10962960 | 0.86 | CISD1 (0.50) | CISD1KDM4ETSHRHSD17B10CLK4 | |
| SCHEMBL10962539 | 0.84 | CISD1 (0.66) | CISD1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL11217820 | 0.82 | CISD1 (0.48) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11381881 | 0.77 | CA1 (0.51) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11075618 | 0.74 | CISD1 (0.39) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11075622 | 0.74 | CISD1 (0.39) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11115185 | 0.74 | CISD1 (0.39) | CISD1CA12CA1CA2CA3 | |
| Sulfuric Acid SCHEMBL11157508 | 0.73 | CA1 (0.50) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11075640 | 0.72 | ALDH1A1 (0.33) | CISD1KDM4EHPGDCA2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056970-B1 | ANTHRANILIC ACIDS SUBSTITUTED BY BASIC GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4478843-A | 5-Phenyltetrazoles and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0051816-B1 | 5-PHENYLTETRAZOLES SUBSTITUTED BY BASIC GROUPS, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | disclosed |
| US-4406895-A | Base-substituted anthranilic acids, a process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-27 | — | — | US | disclosed |
| EP-0051816-A1 | 5-Phenyltetrazoles substituted by basic groups, method for their preparation and their use as drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |