Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 15/20 | 0.46 |
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA12 | O43570 | 13/20 | 0.46 |
| ▸ | CA9 | Q16790 | 11/20 | 0.46 |
| ▸ | CA7 | P43166 | 9/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.46 |
| ▸ | CA3 | P07451 | 7/20 | 0.46 |
| ▸ | CA6 | P23280 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 6/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962539 | 0.86 | CISD1 (0.66) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11226942 | 0.85 | ALDH1A1 (0.52) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11231644 | 0.85 | CISD1 (0.52) | CISD1CA1CA2CA7CA13 | |
| SCHEMBL10963452 | 0.82 | CISD1 (0.47) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11381881 | 0.79 | CA1 (0.51) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11023900 | 0.77 | ALDH1A1 (0.43) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11075622 | 0.76 | CISD1 (0.39) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11115185 | 0.76 | CISD1 (0.39) | CISD1CA1CA2CA12CA9 | |
| SCHEMBL11075618 | 0.76 | CISD1 (0.39) | CISD1CA1CA2CA12CA9 | |
| Sulfuric Acid SCHEMBL11157508 | 0.75 | CA1 (0.50) | CISD1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341773-A | 2,4-Diamino-5-sulfamoylbenzene sulfonic acids and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-27 | — | — | US | disclosed |