Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073229 | 0.84 | MAOA (0.44) | RAB9ANPC1MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL11068104 | 0.83 | AAK1 (0.45) | ALDH1A1GAAHTTAAK1 | |
| SCHEMBL11070649 | 0.78 | ALDH1A1 (0.44) | RAB9ANPC1MAOASLC6A2SLC6A4 | |
| SCHEMBL11075131 | 0.77 | MAOB (0.47) | RAB9ANPC1MAOACYP1A2ALDH1A1 | |
| SCHEMBL7348534 | 0.77 | NPC1 (0.53) | RAB9ANPC1MAOACYP1A2ADRA2A | |
| SCHEMBL11071902 | 0.76 | MAOA (0.44) | RAB9ANPC1MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL11068819 | 0.76 | MAOA (0.44) | RAB9AMAOAALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11073271 | 0.75 | MAOA (0.42) | RAB9ANPC1MAOAHTR2BALDH1A1 | |
| SCHEMBL11073964 | 0.74 | MAOA (0.47) | RAB9ANPC1MAOACYP1A2ALDH1A1 | |
| SCHEMBL11071298 | 0.74 | MAOA (0.47) | RAB9ANPC1MAOACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474786-A | CONGESTIVE HEART FAILURE | SCHERING CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0102046-A1 | Tricyclic lactams, method for making them, pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |