Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075627 | 0.84 | RAB9A (0.45) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11075131 | 0.78 | MAOB (0.47) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11073964 | 0.78 | MAOA (0.47) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11071298 | 0.78 | MAOA (0.47) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11070649 | 0.76 | ALDH1A1 (0.44) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11068699 | 0.75 | KDM4E (0.46) | MAOAMAOBALDH1A1MAPTRAB9A | |
| SCHEMBL11071902 | 0.75 | MAOA (0.44) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11068819 | 0.75 | MAOA (0.44) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11073271 | 0.74 | MAOA (0.42) | MAOAMAOBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11067060 | 0.73 | MAOA (0.41) | MAOAMAOBALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474786-A | CONGESTIVE HEART FAILURE | SCHERING CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0102046-A1 | Tricyclic lactams, method for making them, pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |