Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18479371 | 0.82 | KDM4E (0.61) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL20821160 | 0.82 | KDM4E (0.61) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL16168708 | 0.78 | LMNA (0.52) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL13359801 | 0.78 | TDP1 (0.48) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL6273718 | 0.77 | ALOX15 (0.46) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL13359729 | 0.77 | ALOX15 (0.46) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL16736818 | 0.74 | TRPA1 (0.69) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL17424101 | 0.74 | TRPA1 (0.69) | KDM4ETDP1RECQLMAPTLMNA | |
| SCHEMBL13224269 | 0.74 | TSHR (0.59) | TDP1ALOX15NFKB1BLMTSHR | |
| SCHEMBL27929145 | 0.74 | KDM4E (0.48) | KDM4ETDP1RECQLMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127208-A1 | Process for preparing substituted 2,3-dihydrobenzofuran | ENICHIMICA SECONDARIA S.p.A. (IT) | 1984-12-05 | — | — | EP | disclosed |