Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10614118 | 0.99 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BTRPV1 | |
| Water SCHEMBL10614131 | 0.99 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BTRPV1 | |
| SCHEMBL10967358 | 0.84 | ADRA1A (0.61) | ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10617135 | 0.80 | ADRA1D (0.49) | ADRA1DADRA1AADRA1B | |
| SCHEMBL10614226 | 0.77 | KDM4E (0.64) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10616129 | 0.77 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10616121 | 0.77 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10614741 | 0.77 | ADRA1D (0.50) | ADRA1DADRA1AADRA1B | |
| SCHEMBL10614842 | 0.76 | EHMT2 (0.61) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10616130 | 0.76 | EHMT2 (0.60) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435401-A | 4-Amino-6,7-dimethoxy-2-(4-heteroaryl-piperazino)quinazoline antihypertensives | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0100200-A1 | 2-Substituted 4-amino-6,7-dimethoxyquinolines | Pfizer Limited (GB) | 1984-02-08 | — | — | EP | disclosed |