Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074803 | 0.85 | SMN1; SMN2 (0.58) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11185924 | 0.82 | L3MBTL1 (0.46) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11195982 | 0.81 | THRB (0.60) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11076535 | 0.81 | L3MBTL1 (0.46) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11081956 | 0.80 | SMN1; SMN2 (0.52) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11075577 | 0.79 | L3MBTL1 (0.60) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11189760 | 0.78 | MAPT (0.51) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11080433 | 0.78 | L3MBTL1 (0.49) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11071349 | 0.78 | L3MBTL1 (0.49) | THRBSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL11079931 | 0.78 | L3MBTL1 (0.49) | THRBSMN1; SMN2L3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043858-B1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4386092-A | IMMUNOMODULATORY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| EP-0043858-A1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | disclosed |