Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074803 | 0.91 | SMN1; SMN2 (0.58) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11071349 | 0.88 | L3MBTL1 (0.49) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11081956 | 0.88 | SMN1; SMN2 (0.52) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11080433 | 0.88 | L3MBTL1 (0.49) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11075105 | 0.84 | THRB (0.52) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11077267 | 0.84 | L3MBTL1 (0.46) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11078473 | 0.84 | L3MBTL1 (0.51) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11187294 | 0.83 | L3MBTL1 (0.45) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL1646584 | 0.78 | SMN1; SMN2 (0.55) | L3MBTL1THRBSMN1; SMN2MAPTHTT | |
| SCHEMBL11075893 | 0.78 | THRB (0.58) | L3MBTL1THRBSMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043858-B1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4386092-A | IMMUNOMODULATORY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| EP-0043858-A1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | disclosed |