SCHEMBL11075952

SCHEMBL11075952

Clc1ccccc1CC1OCCO1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
RECQL P46063 1/20 0.49
TAAR1 Q96RJ0 2/20 0.46
CYP2A13 Q16696 1/20 0.44
PKM P14618 2/20 0.44
IDO1 P14902 2/20 0.43
PNMT P11086 1/20 0.43
MGLL Q99685 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.41
CXCR4 P61073 1/20 0.41
SLC6A2 P23975 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29910934 1.00 KMT2A (0.49) KMT2AMEN1TP53CYP3A4CYP2D6
SCHEMBL3534749 0.78 TAAR1 (0.51) KMT2AMEN1TP53CYP3A4CYP2D6
SCHEMBL29910988 0.77 CYP2A13 (0.47) KMT2AMEN1CYP3A4CYP2C9CYP2C19
SCHEMBL29911185 0.76 CYP2A13 (0.44) KMT2AMEN1CYP2D6TAAR1CYP2A13
SCHEMBL1968823 0.76 PKM (0.46) KMT2ATAAR1CYP2A13PKMIDO1
SCHEMBL9827642 0.76 SIRT2 (0.37) KMT2AMEN1TP53CYP3A4CYP2D6
SCHEMBL1228199 0.76 CYP2A13 (0.44) RECQLTAAR1CYP2A13IDO1SLC6A2
SCHEMBL29910990 0.73 CYP2D6 (0.54) KMT2AMEN1CYP2D6CYP2C9CYP2C19
SCHEMBL7789755 0.73 SLC6A2 (0.42) KMT2AMEN1TP53CYP3A4CYP2D6
SCHEMBL1119464 0.72 MEN1 (0.58) KMT2AMEN1TP53CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431851-A ANALGESICS, ANTIDEPRESSANTS DELALANDE S.A. (FR) 1984-02-14 US disclosed