SCHEMBL3534749

SCHEMBL3534749

Clc1ccccc1CC1CO1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.51
IDO1 P14902 3/20 0.45
PNMT P11086 1/20 0.45
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42
CYP2A13 Q16696 1/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
KCNH2 Q12809 1/20 0.40
ALDH1A1 P00352 1/20 0.39
ATM Q13315 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
PKM P14618 2/20 0.39
CXCR4 P61073 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6480647 0.84 TDP1 (0.45) TAAR1MEN1TP53CYP3A4KMT2A
SCHEMBL29826970 0.84 TDP1 (0.45) TAAR1MEN1TP53CYP3A4KMT2A
SCHEMBL28859704 0.82 TAAR1 (0.37) TAAR1PNMTKDM4EHTTCYP2A13
SCHEMBL13116361 0.81 HSP90AA1 (0.45) TAAR1PNMTCYP2A13MEN1TP53
SCHEMBL31076452 0.81 TAAR1 (0.36) TAAR1IDO1PNMTKDM4EHTT
SCHEMBL11455975 0.80 TAAR1 (0.48) TAAR1IDO1PNMTKDM4EHTT
SCHEMBL2675606 0.78 TDP1 (0.41) TAAR1MEN1TP53CYP3A4CYP2C9
SCHEMBL28454337 0.78 TDP1 (0.41) TAAR1MEN1TP53CYP3A4KMT2A
SCHEMBL30607492 0.78 TDP1 (0.41) TAAR1MEN1TP53CYP3A4KMT2A
SCHEMBL11075952 0.78 KMT2A (0.49) TAAR1IDO1PNMTKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762369-B1 A PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL LTD (IN) 2024-12-11 EP disclosed
CN-117126044-B Microwave-assisted synthesis method of methyl ketone compound 延边大学 2024-01-26 CN disclosed
CN-117126044-A Microwave-assisted synthesis method of methyl ketone compound 延边大学 2023-11-28 CN disclosed
US-11634394-B2 Process for preparation of fungicidally active triazole compounds UPL LTD (IN) 2023-04-25 US disclosed
US-20220089552-A1 PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL LTD (IN) 2022-03-24 US disclosed
US-7642277-B2 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-01-05 US disclosed
US-7642277-B2 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-01-05 US disclosed
US-7642277-B2 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-01-05 US disclosed
EP-1569919-A2 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS Boehringer Ingelheim International GmbH (DE) 2005-09-07 EP disclosed
US-20050054639-A1 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-03-10 US disclosed
WO-2004050643-A2 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11634394-B2 Process for preparation of fungicidally active triazole compounds CAT, TYR, TH TAAR1 267/4885IDO1 993/4885PNMT 123/4885
US-20050054639-A1 Non-nucleoside reverse transcriptase inhibitors NAT1, SUB1, RTF2 TAAR1 1196/4885IDO1 304/4885PNMT 917/4885
US-20220089552-A1 PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS CAT, TYR, TH TAAR1 267/4885IDO1 993/4885PNMT 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.