SCHEMBL7789755

SCHEMBL7789755

Clc1ccccc1CC1NCCO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.42
IDO1 P14902 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CYP2A13 Q16696 1/20 0.39
CHRNA7 P36544 1/20 0.37
PNMT P11086 1/20 0.37
PKM P14618 1/20 0.37
SLC6A3 Q01959 3/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
KDM4E B2RXH2 2/20 0.36
HTT P42858 1/20 0.36
SLC6A4 P31645 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57767 0.75 POLB (0.44) SLC6A2SLC6A3ADRA1AHTR2B
SCHEMBL3314458 0.74 SLC6A2 (0.52) SLC6A2SLC6A3ADRA1AHTR2BSLC6A4
SCHEMBL11075952 0.73 KMT2A (0.49) SLC6A2IDO1TAAR1CYP2A13PNMT
SCHEMBL29910934 0.73 KMT2A (0.49) SLC6A2IDO1TAAR1CYP2A13PNMT
SCHEMBL3534749 0.71 TAAR1 (0.51) IDO1TAAR1CYP2A13PNMTPKM
SCHEMBL28159803 0.69 PARP1 (0.35) SLC6A2TAAR1CHRNA7PNMTSLC6A3
SCHEMBL6796105 0.68 HTR6 (0.55)
SCHEMBL18019793 0.68 HTR6 (0.55)
SCHEMBL18019790 0.68 HTR6 (0.55)
SCHEMBL3161884 0.67 GBA1 (0.56) SLC6A2SLC6A3SLC6A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820978-B1 Aqueous dispersions and their use for treating textiles CLARIANT FINANCE BVI LTD (VG) 2001-12-19 EP disclosed
EP-0820978-A1 Aqueous dispersions and their use for treating textiles Clariant Finance (BVI) Limited (VG) 1998-01-28 EP disclosed