Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879104 | 0.89 | LMNA (0.54) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL29638140 | 0.87 | LMNA (0.53) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9166728 | 0.87 | LMNA (0.53) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL21160461 | 0.83 | LMNA (0.53) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9074053 | 0.82 | LMNA (0.48) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL9073589 | 0.80 | NPSR1 (0.47) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL7133642 | 0.79 | LMNA (0.46) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL13925442 | 0.79 | ALDH1A1 (0.48) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL2393621 | 0.77 | LMNA (0.57) | LMNAALDH1A1NPSR1TSHRUSP2 | |
| SCHEMBL15702659 | 0.76 | ALDH1A1 (0.48) | LMNAALDH1A1NPSR1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490394-A | ANIMAL FEEDSTUFFS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-12-25 | — | — | US | disclosed |
| US-4363910-A | 2,2-Dimethyl-1,2-dihydroquinoline derivatives useful as antioxidants | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-12-14 | — | — | US | disclosed |