Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | RAC1 | P63000 | 3/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081346 | 0.85 | PARP1 (0.39) | SHMT2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11081006 | 0.81 | TLR7 (0.40) | SHMT2KDM4EMAPTMEN1NPC1 | |
| SCHEMBL11075432 | 0.75 | SHMT2 (0.48) | SHMT2KDM4EMAPTPDGFRBPDGFRA | |
| SCHEMBL11433633 | 0.74 | TGFBR1 (0.47) | KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11497347 | 0.74 | PARP1 (0.38) | SHMT2KDM4EMAPTCRHR1MEN1 | |
| SCHEMBL11448810 | 0.72 | SHMT2 (0.48) | SHMT2KDM4EMAPTABCC1MEN1 | |
| SCHEMBL11077056 | 0.72 | GRIK2 (0.44) | KDM4EMAPTTDP1MEN1NPC1 | |
| SCHEMBL30424849 | 0.68 | KDM4E (0.49) | SHMT2KDM4EMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11077145 | 0.68 | PARP1 (0.52) | SHMT2KDM4EMAPTMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL11086416 | 0.67 | PARP1 (0.51) | SHMT2KDM4EMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |