Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 4/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081346 | 0.86 | PARP1 (0.39) | GRIK2GRIK1DYRK1AMAPTSMN1; SMN2 | |
| SCHEMBL11086321 | 0.85 | GRIK2 (0.52) | GRIK2GRIK1NPSR1POLBTDP1 | |
| SCHEMBL11497347 | 0.79 | PARP1 (0.38) | GRIK2GRIK1TSPODYRK1AMAPT | |
| SCHEMBL11076799 | 0.75 | CASR (0.50) | GRIK2GRIK1NPSR1TSPODYRK1A | |
| SCHEMBL11079618 | 0.74 | GRIK2 (0.52) | GRIK2GRIK1NPSR1POLBMAPT | |
| SCHEMBL11073152 | 0.73 | HSD17B10 (0.44) | TDP1MAPTPTGER4SMN1; SMN2KDM4E | |
| SCHEMBL11290683 | 0.73 | GRIK2 (0.47) | GRIK2GRIK1NPSR1POLBTDP1 | |
| SCHEMBL11076164 | 0.72 | SHMT2 (0.42) | TDP1MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11086416 | 0.69 | PARP1 (0.51) | GRIK2GRIK1DYRK1AMAPTSMN1; SMN2 | |
| SCHEMBL11081006 | 0.69 | TLR7 (0.40) | MAPTPTGER4SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |