Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077918 | 0.88 | RAB9A (0.49) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| Pirazolac SCHEMBL153631 | 0.87 | KDM4E (0.51) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| Pirazolac SCHEMBL10952997 | 0.86 | KDM4E (0.50) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL11764061 | 0.83 | KDM4E (0.50) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL11765077 | 0.82 | RPA1 (0.46) | PPP1CAKDM4EALDH1A1HTTDRD2 | |
| SCHEMBL11399779 | 0.82 | RAB9A (0.44) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL11073884 | 0.81 | CNR1 (0.43) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL10880429 | 0.81 | KMT2A (0.48) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL11764727 | 0.80 | RAB9A (0.64) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL11443525 | 0.80 | KDM4E (0.56) | KMT2AKDM4EALDH1A1DRD2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022906-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |