Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764061 | 0.94 | KDM4E (0.50) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| Pirazolac SCHEMBL153631 | 0.94 | KDM4E (0.51) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11399779 | 0.94 | RAB9A (0.44) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| Pirazolac SCHEMBL10952997 | 0.92 | KDM4E (0.50) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11764727 | 0.91 | RAB9A (0.64) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11078308 | 0.89 | MEN1 (0.43) | RAB9AKMT2AMEN1HTTSRC | |
| SCHEMBL11076213 | 0.88 | PPP1CA (0.49) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11443525 | 0.86 | KDM4E (0.56) | RAB9AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11764002 | 0.84 | KDM4E (0.60) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10952988 | 0.83 | PTGS2 (0.43) | RAB9AKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | claimed |
| EP-0022906-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |