Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645532 | 0.98 | TP53 (0.55) | TP53POLBLMNANOTUMPTGDR2 | |
| SCHEMBL11066272 | 0.83 | TP53 (0.51) | TP53POLBLMNANOTUMKDM4E | |
| SCHEMBL23498885 | 0.81 | TP53 (0.49) | TP53POLBLMNANOTUMKDM4E | |
| SCHEMBL7678717 | 0.80 | LMNA (0.57) | TP53POLBLMNAKDM4EL3MBTL1 | |
| SCHEMBL11241475 | 0.77 | TP53 (0.37) | TP53POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL11214797 | 0.77 | PTGS2 (0.54) | TP53POLBLMNAALDH1A1 | |
| SCHEMBL23498965 | 0.75 | TP53 (0.44) | TP53POLBLMNANOTUMKDM4E | |
| SCHEMBL9959156 | 0.72 | TP53 (0.40) | TP53POLBLMNANOTUMKDM4E | |
| SCHEMBL5553127 | 0.71 | TP53 (0.39) | TP53POLBLMNANOTUMKDM4E | |
| SCHEMBL21810001 | 0.69 | TP53 (0.43) | TP53POLBLMNANOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451658-A | DECARBOXYLATION WITH MINERAL ACID, ALKANOL, AND WATER | ETHYL CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| WO-1982001552-A1 | PROCESS FOR PRODUCING SUBSTITUTED PYRROLES | ETHYL CORP (US) | 1982-05-13 | — | — | WO | disclosed |
| EP-0051442-A1 | Process for producing substituted pyrroles | ETHYL CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |