Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068985 | 0.90 | CNR1 (0.50) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL10973972 | 0.87 | CNR1 (0.57) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL11076067 | 0.84 | CNR1 (0.48) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL11074709 | 0.83 | CNR1 (0.56) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL10974998 | 0.82 | CNR1 (0.49) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL11081687 | 0.82 | CNR1 (0.59) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL11071403 | 0.81 | CNR1 (0.49) | CNR1CNR2ALDH1A1PDE4DPDE4B | |
| SCHEMBL11081203 | 0.81 | CNR1 (0.51) | CNR1CNR2HPGDALDH1A1MAPT | |
| SCHEMBL11072620 | 0.81 | CNR1 (0.53) | CNR1CNR2ADORA1PDE1APDE1B | |
| SCHEMBL11071848 | 0.81 | CNR1 (0.57) | CNR1CNR2ADORA1PDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |