Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115601 | 0.92 | ALDH1A1 (0.46) | SMN1; SMN2KDM4ETARBP2KMT2AMEN1 | |
| SCHEMBL11080825 | 0.90 | HSD17B10 (0.53) | SMN1; SMN2KDM4ETARBP2KMT2AMEN1 | |
| SCHEMBL2824426 | 0.90 | ALDH1A1 (0.45) | SMN1; SMN2KDM4ETRPM8KMT2AMEN1 | |
| SCHEMBL13116096 | 0.89 | ALDH1A1 (0.48) | SMN1; SMN2KDM4EKMT2AMEN1POLB | |
| SCHEMBL13115485 | 0.89 | TARBP2 (0.48) | SMN1; SMN2KDM4ETARBP2KMT2AMEN1 | |
| SCHEMBL13115629 | 0.89 | HSD17B10 (0.41) | SMN1; SMN2KDM4EKMT2AMEN1POLB | |
| SCHEMBL13116025 | 0.89 | POLB (0.44) | SMN1; SMN2KDM4EKMT2AMEN1POLB | |
| SCHEMBL13116028 | 0.87 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EKMT2AMEN1POLB | |
| SCHEMBL13115622 | 0.87 | MAPK1 (0.50) | SMN1; SMN2KDM4EKMT2AMEN1POLB | |
| SCHEMBL13115648 | 0.86 | ALDH1A1 (0.43) | KDM4EKMT2AMEN1POLBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065145-B1 | NOVEL THIENYLOXAZOLYLACETIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4460596-A | Thienyloxazolylacetic acid derivatives and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0065145-A1 | Novel thienyloxazolylacetic acid derivatives and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1982-11-24 | — | — | EP | disclosed |