Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115601 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TP53GAANPC1RAB9A | |
| SCHEMBL11076346 | 0.90 | SMN1; SMN2 (0.51) | ALDH1A1TP53NPC1MEN1KMT2A | |
| SCHEMBL13116025 | 0.90 | POLB (0.44) | ALDH1A1GAANPC1RAB9AMEN1 | |
| SCHEMBL11080825 | 0.90 | HSD17B10 (0.53) | ALDH1A1GAANPC1RAB9AMEN1 | |
| SCHEMBL13115485 | 0.89 | TARBP2 (0.48) | ALDH1A1TP53GAANPC1RAB9A | |
| SCHEMBL13115629 | 0.88 | HSD17B10 (0.41) | ALDH1A1TP53GAANPC1RAB9A | |
| SCHEMBL13116027 | 0.86 | TNFRSF1A (0.44) | ALDH1A1TP53USP2NPC1RAB9A | |
| SCHEMBL13115883 | 0.85 | GAA (0.52) | ALDH1A1TP53USP2GAAMEN1 | |
| SCHEMBL13115499 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TP53USP2GAAMEN1 | |
| SCHEMBL2817791 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1TP53USP2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065145-B1 | NOVEL THIENYLOXAZOLYLACETIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1984-10-03 | — | — | EP | claimed |
| US-4460596-A | Thienyloxazolylacetic acid derivatives and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-07-17 | — | — | US | claimed |
| EP-0065145-A1 | Novel thienyloxazolylacetic acid derivatives and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1982-11-24 | — | — | EP | claimed |
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | HONGU MITSUYA | 2010-10-07 | — | — | US | disclosed |
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | HONGU MITSUYA | 2010-10-07 | — | — | US | disclosed |
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | HONGU MITSUYA | 2010-10-07 | — | — | US | disclosed |
| US-7759373-B2 | Large conductance calcium-activated K channel opener | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7759373-B2 | Large conductance calcium-activated K channel opener | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7759373-B2 | Large conductance calcium-activated K channel opener | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20040127527-A1 | Large conductance calcium-activated k channel opener | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-0065145-B1 | NOVEL THIENYLOXAZOLYLACETIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4460596-A | Thienyloxazolylacetic acid derivatives and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0065145-A1 | Novel thienyloxazolylacetic acid derivatives and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | KCNN3, KCNN2, KCNN1 | ALDH1A1 4600/4885TP53 3724/4885USP2 3553/4885 |
| US-20040127527-A1 | Large conductance calcium-activated k channel opener | KCNN1, KCNN4, KCNN3 | ALDH1A1 4245/4885TP53 4394/4885USP2 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.