Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115601 | 0.92 | ALDH1A1 (0.46) | HSD17B10TARBP2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL11076346 | 0.90 | SMN1; SMN2 (0.51) | HSD17B10TARBP2MAPTSMN1; SMN2KMT2A | |
| SCHEMBL13115629 | 0.90 | HSD17B10 (0.41) | HSD17B10TDP1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2824426 | 0.90 | ALDH1A1 (0.45) | HSD17B10MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13115485 | 0.89 | TARBP2 (0.48) | HSD17B10TARBP2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL13115681 | 0.88 | MAPT (0.43) | HSD17B10TDP1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL13116025 | 0.88 | POLB (0.44) | HSD17B10MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13115652 | 0.85 | HSD17B10 (0.54) | HSD17B10TARBP2TDP1MAPTSMN1; SMN2 | |
| SCHEMBL13115597 | 0.85 | KDM4E (0.47) | HSD17B10MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13116096 | 0.84 | ALDH1A1 (0.48) | HSD17B10TDP1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065145-B1 | NOVEL THIENYLOXAZOLYLACETIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4460596-A | Thienyloxazolylacetic acid derivatives and process for preparing | TANABE SEIYAKU CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0065145-A1 | Novel thienyloxazolylacetic acid derivatives and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1982-11-24 | — | — | EP | disclosed |