SCHEMBL11076376

SCHEMBL11076376

O=CC(O)C(O)C(O)C(O)CCl

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.34
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419475 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL4426222 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL1131549 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL11077622 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL27994793 0.92 MPI (0.35) MPIAKR1B1
SCHEMBL4278103 0.92 MPI (0.35) MPIAKR1B1
Demannose SCHEMBL11074350 0.91 LMNA (0.46) MPIAKR1B1
Galactose SCHEMBL9515293 0.91 LMNA (0.46) MPIAKR1B1
SCHEMBL7148720 0.81 MPI (0.32) MPI
SCHEMBL23072256 0.78 AKR1B1 (0.37) MPIAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0015652-B1 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1983-01-19 EP claimed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP claimed
CN-102076865-B The antibody reduced for the manufacture of core fucosylation and the method and composition of antibody derivatives SEATTLE GENETICS, INC. (US) 2016-03-16 CN disclosed
CN-102076865-A Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation SEATTLE GENETICS INC 2011-05-25 CN disclosed
US-4442123-A 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1984-04-10 US disclosed
US-4442123-A 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1984-04-10 US disclosed
EP-0015652-B1 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1983-01-19 EP disclosed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP disclosed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP disclosed