SCHEMBL11077622

SCHEMBL11077622

O=C[C@H](O)[C@H](O)[C@H](O)[C@H](O)CCl

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.34
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419475 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL4426222 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL1131549 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL11076376 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL27994793 0.92 MPI (0.35) MPIAKR1B1
SCHEMBL4278103 0.92 MPI (0.35) MPIAKR1B1
Demannose SCHEMBL11074350 0.91 LMNA (0.46) MPIAKR1B1
Galactose SCHEMBL9515293 0.91 LMNA (0.46) MPIAKR1B1
SCHEMBL7148720 0.81 MPI (0.32) MPI
SCHEMBL23072256 0.78 AKR1B1 (0.37) MPIAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180180626-A1 A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT STC BIOLOGICS INC (US) 2018-06-28 US disclosed
US-9868973-B2 Method for optimizing post-translational modifications on recombinant proteins STC BIOLOGICS, INC. (US) 2018-01-16 US disclosed
US-20160340706-A1 Method for Optimizing Post-Translational Modifications on Recombinant Proteins STC BIOLOGICS, INC. 2016-11-24 US disclosed
EP-3094639-A1 METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS Leszcyniecka, Magdalena (US) 2016-11-23 EP disclosed
WO-2015106276-A1 METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS LESZCYNIECKA MAGDALENA (US) 2015-07-16 WO disclosed
US-4442123-A 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1984-04-10 US disclosed
EP-0015652-B1 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1983-01-19 EP disclosed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP disclosed