SCHEMBL4419475

SCHEMBL4419475

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CCl

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.34
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426222 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL1131549 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL11077622 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL11076376 1.00 MPI (0.34) MPIAKR1B1
SCHEMBL27994793 0.92 MPI (0.35) MPIAKR1B1
SCHEMBL4278103 0.92 MPI (0.35) MPIAKR1B1
Demannose SCHEMBL11074350 0.91 LMNA (0.46) MPIAKR1B1
Galactose SCHEMBL9515293 0.91 LMNA (0.46) MPIAKR1B1
SCHEMBL7148720 0.81 MPI (0.32) MPI
SCHEMBL23072256 0.78 AKR1B1 (0.37) MPIAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8552176-B2 Glycosylated chlorambucil analogs and uses thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-10-08 US claimed
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis INTERSTITIAL THERAPEUTICS (CH) 2009-12-31 US claimed
EP-1789030-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
EP-1789107-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
WO-2006024488-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024490-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024491-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024492-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
EP-0130054-B1 NOVEL FRUCTOSYLTRANSFERASE, PROCESS FOR THE PREPARATION OF FRUCTOSYL DISACCHARIDES, AND A NOVEL HALOSUCROSE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1990-03-07 EP claimed
US-4617269-A WITH TRANSFERASE ENZYMES DERIVED FROM BACILLUS TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1986-10-14 US claimed
EP-0130054-A2 Novel Fructosyltransferase, process for the preparation of Fructosyl disaccharides, and a novel halosucrose TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-01-02 EP claimed
US-4225590-A Male fertility-inhibiting compositions of 6-chlorodeoxy-saccharides TATE & LYLE LIMITED (GB) 1980-09-30 US claimed
JP-10042883-A None JP disclosed
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis INTERSTITIAL THERAPEUTICS (CH) 2009-12-31 US disclosed
US-20070292478-A1 Medical Implant Provided with Inhibitors of Atp Synthesis INTERSTITIAL THERAPEUTICS (CH) 2007-12-20 US disclosed
EP-1789107-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP disclosed
US-4226749-A POLYETHYLENIMINE, METHACRYLIC ACID INTERPOLYMER MANUFACTURE DE PRODUITS CHIMIQUES PROTEX S.A. (FR) 1980-10-07 US disclosed
US-4225590-A Male fertility-inhibiting compositions of 6-chlorodeoxy-saccharides TATE & LYLE LIMITED (GB) 1980-09-30 US disclosed
EP-0015652-A1 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1980-09-17 EP disclosed
EP-0015757-A1 Process for the preparation of chlorodeoxysugars TATE & LYLE PATENT HOLDINGS LIMITED (BM) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis ATP5ME, ATP5F1A, ATP5MG MPI 193/4885AKR1B1 2102/4885
US-20070292478-A1 Medical Implant Provided with Inhibitors of Atp Synthesis ATP5F1A, ATP5ME, ATP5MG MPI 365/4885AKR1B1 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.