SCHEMBL11076504

SCHEMBL11076504

Cc1nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)nc(C)c1Br

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 1/20 0.32
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11072808 0.91 GAA (0.31) ALOX15GAA
SCHEMBL11071268 0.89 GAA (0.30) GAA
SCHEMBL11069312 0.87
SCHEMBL4047513 0.87 GAA (0.43) ALOX15ALDH1A1RAB9AGAA
SCHEMBL11076837 0.83
SCHEMBL11082139 0.83
SCHEMBL6313348 0.82 GAA (0.48) ALOX15ALDH1A1GAA
SCHEMBL3304539 0.81 GAA (0.33) ALOX15GAA
SCHEMBL11073812 0.80 GAA (0.38) GAA
SCHEMBL11072278 0.79 GAA (0.31) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023140-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP claimed