SCHEMBL4047513

SCHEMBL4047513

Cc1cc(C)nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)n1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
ALOX15 P16050 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RECQL P46063 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11072808 0.89 GAA (0.31) GAAALOX15
Sulfometuron SCHEMBL9551981 0.87 LMNA (0.36) GAAALOX15NPC1RAB9AMAPT
SCHEMBL11076504 0.87 ALOX15 (0.33) GAAALOX15RAB9AALDH1A1
SCHEMBL11071268 0.87 GAA (0.30) GAA
SCHEMBL6313348 0.86 GAA (0.48) GAAALOX15MAPTLMNAHTT
Sulfometuron Methyl SCHEMBL9394949 0.85 GAA (0.38) GAAALOX15NPC1MAPTLMNA
SCHEMBL11069312 0.85
SCHEMBL3304539 0.83 GAA (0.33) GAAALOX15
Sulfometuron SCHEMBL9540465 0.83 LMNA (0.35) GAAALOX15NPC1MAPTLMNA
SCHEMBL8712354 0.82 GAA (0.39) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575489-B1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION DU PONT (US) 1997-07-02 EP claimed
EP-0637909-B1 REVERSIBLE AGRICULTURAL GEL AND PASTE FORMULATIONS DU PONT (US) 1997-02-26 EP claimed
EP-0471284-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1995-01-18 EP claimed
US-7622641-B2 Methods and compositions for providing tolerance to multiple herbicides PIONEER HI-BRED INT'L., INC. (US) 2009-11-24 US disclosed
US-20070079393-A1 Methods and compositions for providing tolerance to multiple herbicides PIONEER HI-BRED INTERNATIONAL, INC. (US) 2007-04-05 US disclosed
EP-0683157-B1 Sulfonylaminocarbonyltriazolinones as herbicides BAYER CROPSCIENCE AG (DE) 2004-05-26 EP disclosed
US-6150301-A Chemical abscission of fruits at low application rates WILCOX MERRILL (US) 2000-11-21 US disclosed
EP-0507171-B1 Sulfonylaminocarbonyltriazolinones with oxygen-bound substituents BAYER AG (DE) 1997-10-01 EP disclosed
US-5616789-A CHEMICAL INTERMEDIATE FOR 2-PHENYLPYRIDAZINE HERBICIDE MONSANTO COMPANY (US) 1997-04-01 US disclosed
US-5559080-A 3-phenoxypyridazines, herbicidal compositions and uses thereof MONSANTO COMPANY (US) 1996-09-24 US disclosed
EP-0422469-B1 Sulfonylaminocarbonyltriazolinones BAYER AG (DE) 1996-05-08 EP disclosed
EP-0432200-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-19 EP disclosed
EP-0422469-A2 Sulfonylaminocarbonyltriazolinones BAYER AG (DE) 1991-04-17 EP disclosed
EP-0419831-A2 Substituted sulfonylaminoazoles BAYER AG (DE) 1991-04-03 EP disclosed
US-4913722-A HERBICIDES ICI AMERICAS INC. (US) 1990-04-03 US disclosed
EP-0360441-A1 Water-soluble or water-dispersible pesticide granules E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-28 EP disclosed
WO-1990002486-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-22 WO disclosed
EP-0303153-A2 1-Aryl pyrazoles BAYER AG (DE) 1989-02-15 EP disclosed
EP-0297427-A2 1-Arylpyrazole BAYER AG (DE) 1989-01-04 EP disclosed
EP-0267412-A1 Imidazo-pyrrolo-pyridine derivatives BAYER AG (DE) 1988-05-18 EP disclosed