SCHEMBL11072808

SCHEMBL11072808

Cc1nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)nc(C)c1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11069312 0.91
SCHEMBL11076504 0.91 ALOX15 (0.33) GAAALOX15
SCHEMBL11071268 0.91 GAA (0.30) GAA
SCHEMBL4047513 0.89 GAA (0.43) GAAALOX15
SCHEMBL11076837 0.85
SCHEMBL11082139 0.84
SCHEMBL6313348 0.84 GAA (0.48) GAAALOX15
SCHEMBL3304539 0.83 GAA (0.33) GAAALOX15
SCHEMBL11072278 0.83 GAA (0.31) GAA
SCHEMBL11073812 0.82 GAA (0.38) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023140-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP claimed