Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075613 | 0.84 | IDO1 (0.45) | CNR1CNR2CYP1A2MAPTHPGD | |
| SCHEMBL11025485 | 0.82 | KDM4E (0.46) | CNR1CNR2CYP2C19MAPTHPGD | |
| SCHEMBL11078414 | 0.77 | IDO1 (0.41) | CYP1A2CYP3A4CYP2C19CYP2C9HPGD | |
| SCHEMBL10614728 | 0.77 | CNR1 (0.52) | CNR1CNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11685404 | 0.77 | CNR1 (0.47) | CNR1CNR2TLR8MAPTHPGD | |
| SCHEMBL11685397 | 0.77 | CNR1 (0.47) | CNR1CNR2TLR8MAPTHPGD | |
| SCHEMBL731902 | 0.76 | ALDH1A1 (0.67) | CNR1CNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30301306 | 0.76 | ALDH1A1 (0.67) | CNR1CNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22181933 | 0.75 | SIRT1 (0.54) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL27467257 | 0.74 | CNR1 (0.56) | CNR1CNR2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |