Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076680 | 0.82 | CNR1 (0.49) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL11075613 | 0.81 | IDO1 (0.45) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL11078414 | 0.76 | IDO1 (0.41) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL6753421 | 0.74 | ALDH1A1 (0.77) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL22181933 | 0.72 | SIRT1 (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11080086 | 0.71 | IDO1 (0.45) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL29193153 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDTSHR | |
| Alcohol SCHEMBL9615112 | 0.69 | THRB (0.51) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL103998 | 0.69 | THRB (0.59) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9507918 | 0.67 | THRB (0.58) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041630-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, THE PROCESS FOR PREPARING THEM, THE COMPOUNDS FOR USE AS ANTIINFLAMMATORY AGENTS AND COMPOSITIONS CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1985-03-13 | — | — | EP | disclosed |
| US-4411907-A | ANALGESICS, ANTIPYRETICS | GRUPPO LEPETIT, S.P.A. (IT) | 1983-10-25 | — | — | US | disclosed |
| EP-0041630-A1 | New 3H-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them | GRUPPO LEPETIT S.P.A. (IT) | 1981-12-16 | — | — | EP | disclosed |