SCHEMBL11076756

SCHEMBL11076756

O=C(Oc1ccccc1)N(CC(F)(F)F)C(=O)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PTGES O14684 1/20 0.42
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 4/20 0.40
MEN1 O00255 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MAOB P27338 1/20 0.40
NR1I2 O75469 2/20 0.39
RORA P35398 1/20 0.39
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
NPC1 O15118 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10992834 0.82 L3MBTL1 (0.50) ATMTDP1L3MBTL1PTGESKMT2A
SCHEMBL16681182 0.79 TDP1 (0.44) ATMTDP1L3MBTL1PTGESKMT2A
SCHEMBL22622046 0.77 LMNA (0.48) ATMTDP1L3MBTL1KMT2AMEN1
SCHEMBL16681003 0.77 ATM (0.41) ATMTDP1L3MBTL1KMT2AALDH1A1
SCHEMBL11129161 0.76 TDP1 (0.40) ATMTDP1L3MBTL1KMT2AALDH1A1
SCHEMBL11670899 0.74 L3MBTL1 (0.53) ATMTDP1L3MBTL1PTGESKMT2A
SCHEMBL11212298 0.72 TDP1 (0.61) ATMTDP1L3MBTL1PTGESKMT2A
SCHEMBL31504010 0.72 ATM (0.47) ATMTDP1L3MBTL1PTGESKMT2A
SCHEMBL364109 0.72 CYP19A1 (0.47) ATMTDP1L3MBTL1KMT2AALDH1A1
SCHEMBL27806243 0.70 L3MBTL1 (0.49) ATMTDP1L3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034750-B1 N-SUBSTITUTED IMIDODICARBOXYLIC ACID DIARYL ESTERS AND A PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1984-01-18 EP claimed
US-4451406-A N-Substituted imido-dicarboxylic acid diaryl ester method of preparation BAYER AKTIENGESELLSCHAFT (DE) 1984-05-29 US disclosed
US-4447635-A N-Substituted imido-dicarboxylic acid diaryl ester compounds and herbicide intermediates BAYER AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed