Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114778 | 0.83 | L3MBTL1 (0.41) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL11076756 | 0.76 | ATM (0.50) | TDP1HDAC1HDAC2ATML3MBTL1 | |
| SCHEMBL321643 | 0.74 | FABP7 (0.46) | TDP1HDAC1HDAC2ATML3MBTL1 | |
| SCHEMBL11116570 | 0.73 | MTNR1A (0.41) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL11126610 | 0.73 | L3MBTL1 (0.47) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL11431750 | 0.71 | ZDHHC2 (0.45) | MAPT | |
| SCHEMBL9353461 | 0.71 | TDP1 (0.54) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL9241160 | 0.71 | TDP1 (0.54) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL18073 | 0.71 | TDP1 (0.54) | TDP1ATML3MBTL1CYP19A1MAPT | |
| SCHEMBL9353455 | 0.71 | TDP1 (0.54) | TDP1ATML3MBTL1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034750-B1 | N-SUBSTITUTED IMIDODICARBOXYLIC ACID DIARYL ESTERS AND A PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-01-18 | — | — | EP | claimed |
| EP-0034750-A2 | N-substituted imidodicarboxylic acid diaryl esters and a process for their preparation | BAYER AG (DE) | 1981-09-02 | — | — | EP | claimed |
| EP-0034750-B1 | N-SUBSTITUTED IMIDODICARBOXYLIC ACID DIARYL ESTERS AND A PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-01-18 | — | — | EP | disclosed |
| EP-0034750-A2 | N-substituted imidodicarboxylic acid diaryl esters and a process for their preparation | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |