Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11086416 | 0.89 | PARP1 (0.51) | PARP1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11076059 | 0.85 | TLR7 (0.48) | PARP1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11078271 | 0.83 | PARP1 (0.50) | PARP1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL11086406 | 0.81 | PARP1 (0.46) | PARP1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11081129 | 0.81 | PARP1 (0.48) | PARP1RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL11083854 | 0.80 | PARP1 (0.46) | PARP1SHMT2ADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL11077145 | 0.80 | PARP1 (0.52) | PARP1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11083844 | 0.80 | TLR7 (0.47) | APPPARP1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11440865 | 0.80 | APP (0.47) | APPPARP1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11078229 | 0.80 | PARP1 (0.47) | PARP1KDM4EALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |