Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tomoxiprole SCHEMBL525023 | 0.87 | MAPK9 (0.50) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11085482 | 0.84 | MAPK9 (0.47) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11078304 | 0.83 | MAPK9 (0.47) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11024220 | 0.82 | MAPK9 (0.50) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| Tomoxiprole SCHEMBL6937880 | 0.79 | MAPK9 (0.43) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11089329 | 0.78 | KDM4E (0.65) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11073129 | 0.78 | PARP1 (0.55) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11078399 | 0.78 | MAPK9 (0.48) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11078944 | 0.75 | MAPK9 (0.50) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11079618 | 0.75 | GRIK2 (0.52) | MAPK9MAPK14ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |