Tomoxiprole

Tomoxiprole

SCHEMBL525023

COc1ccc(-c2nc3c4ccccc4ccc3n2C(C)C)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.50
MAPK14 Q16539 1/20 0.50
CASR P41180 2/20 0.45
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
RAB9A P51151 4/20 0.41
KDM4E B2RXH2 3/20 0.41
LMNA P02545 3/20 0.41
TP53 P04637 3/20 0.41
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 2/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tomoxiprole SCHEMBL6937880 0.91 MAPK9 (0.43) MAPK9MAPK14CASRCNR1CNR2
SCHEMBL11078304 0.88 MAPK9 (0.47) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11076902 0.87 MAPK9 (0.46) MAPK9MAPK14CASRCNR1CNR2
SCHEMBL11085482 0.86 MAPK9 (0.47) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11075543 0.86 TLR7 (0.43) CASRMEN1KMT2AALDH1A1MAPT
SCHEMBL11073129 0.83 PARP1 (0.55) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11078399 0.80 MAPK9 (0.48) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11024220 0.80 MAPK9 (0.50) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11078944 0.80 MAPK9 (0.50) MAPK9MAPK14CNR1CNR2MEN1
SCHEMBL11079618 0.80 GRIK2 (0.52) MAPK9MAPK14CNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112770764-B Methods of treating infections using bacteria 因达普特斯治疗有限公司 2024-12-03 CN claimed
EP-3856213-B1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA INDAPTUS THERAPEUTICS INC (US) 2024-03-06 EP claimed
US-20220031768-A1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA INDAPTUS THERAPEUTICS, INC. 2022-02-03 US claimed
US-11147844-B2 Methods of treatment of infections using bacteria DECOY BIOSYSTEMS, INC. (US) 2021-10-19 US claimed
EP-3856213-A1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA Decoy Biosystems, Inc. (US) 2021-08-04 EP claimed
US-20210145763-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD. (AU) 2021-05-20 US claimed
CN-112770764-A Methods of treating infections using bacteria 迪科生物系统公司 2021-05-07 CN claimed
EP-3773651-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE Eye Co Pty Ltd. (AU) 2021-02-17 EP claimed
US-20200101119-A1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA INDAPTUS THERAPEUTICS, INC. 2020-04-02 US claimed
WO-2020069211-A1 METHODS OF TREATMENT OF INFECTIONS USING BACTERIA DECOY BIOSYSTEMS, INC. (US) 2020-04-02 WO claimed
CN-1310721-A Medicine nitrate salts NICOX SA (FR) 2001-08-29 CN claimed
EP-1100805-A1 MEDICINE NITRATE SALTS NICOX S.A. (FR) 2001-05-23 EP claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 WO claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061537-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000006585-A1 MEDICINE NITRATE SALTS NICOX S.A. (FR) 2000-02-10 WO claimed
US-4435417-A ANTIINFLAMMATORY AGENTS GRUPPO LEPETIT S.P.A. (IT) 1984-03-06 US claimed
EP-0012866-B1 NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, PROCESSES FOR PREPARING THEM, COMPOUNDS FOR USE AS ANTIINFLAMMATORY AND ANTIMICROBIAL AGENTS AND COMPOSITIONS FOR THAT USE CONTAINING THEM GRUPPO LEPETIT S.P.A. (IT) 1983-01-19 EP claimed
EP-0012866-A1 New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them GRUPPO LEPETIT S.P.A. (IT) 1980-07-09 EP claimed