Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078304 | 0.89 | MAPK9 (0.47) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| Tomoxiprole SCHEMBL525023 | 0.86 | MAPK9 (0.50) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11076902 | 0.84 | MAPK9 (0.46) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11079618 | 0.81 | GRIK2 (0.52) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11073129 | 0.80 | PARP1 (0.55) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11024220 | 0.79 | MAPK9 (0.50) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| Tomoxiprole SCHEMBL6937880 | 0.79 | MAPK9 (0.43) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11089329 | 0.78 | KDM4E (0.65) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11079355 | 0.78 | ALDH1A1 (0.55) | MAPK9MAPK14KDM4EALDH1A1LMNA | |
| SCHEMBL11078399 | 0.77 | MAPK9 (0.48) | MAPK9MAPK14KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |