Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082533 | 0.86 | DRD2 (0.34) | PLA2G7 | |
| SCHEMBL10847559 | 0.86 | PLA2G7 (0.35) | PLA2G7CYP1A2CYP2D6 | |
| SCHEMBL10848628 | 0.85 | PLA2G7 (0.33) | PLA2G7 | |
| SCHEMBL11182943 | 0.83 | PLA2G7 (0.31) | PLA2G7 | |
| SCHEMBL7736057 | 0.82 | PLA2G7 (0.50) | PLA2G7 | |
| SCHEMBL10618958 | 0.81 | PLA2G7 (0.48) | PLA2G7 | |
| SCHEMBL10851632 | 0.78 | PARP1 (0.31) | CYP2D6 | |
| SCHEMBL10848262 | 0.78 | ACHE (0.36) | — | |
| SCHEMBL10376073 | 0.78 | PLA2G7 (0.42) | PLA2G7 | |
| SCHEMBL7741977 | 0.77 | IDH1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039989-B1 | PYRIMIDONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388317-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-06-14 | — | — | US | disclosed |
| EP-0039989-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-18 | — | — | EP | disclosed |