Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | IAPP | P10997 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12681504 | 0.85 | IAPP (0.56) | ALDH1A1IAPPKMT2AMEN1MAPT | |
| SCHEMBL1874 | 0.82 | ALDH1A1 (0.63) | ALDH1A1IAPPKMT2AMAPTL3MBTL1 | |
| SCHEMBL13267781 | 0.82 | IAPP (0.61) | ALDH1A1IAPPL3MBTL1TDP1F2RL1 | |
| SCHEMBL8746185 | 0.80 | CYP4A11 (0.60) | ALDH1A1IAPPKMT2AMEN1MAPT | |
| SCHEMBL19441526 | 0.80 | IAPP (0.51) | ALDH1A1IAPPL3MBTL1TDP1F2RL1 | |
| Propane SCHEMBL10621118 | 0.80 | ALDH1A1 (0.61) | ALDH1A1IAPPKMT2AMAPTL3MBTL1 | |
| SCHEMBL1058497 | 0.80 | ALDH1A1 (0.67) | ALDH1A1RARBKMT2AMEN1MAPT | |
| SCHEMBL107381 | 0.80 | IAPP (0.65) | ALDH1A1IAPPKMT2AMEN1MAPT | |
| SCHEMBL105765 | 0.80 | TDP1 (0.62) | ALDH1A1IAPPL3MBTL1TDP1F2RL1 | |
| SCHEMBL3367595 | 0.80 | ALDH1A1 (0.63) | ALDH1A1RARBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467112-A | REACTING P-FORMYLBENZOIC ACID OR ESTER WITH KETONE, HYDROGENATION AND REDUCTION OF INTERMEDIATES | KAWASAKI KASEI CHEMICALS LTD. (JP) | 1984-08-21 | — | — | US | disclosed |