SCHEMBL107381

SCHEMBL107381

CCC(=O)CCc1ccc(O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 4/20 0.65
TRPV1 Q8NER1 2/20 0.55
ESR1 P03372 4/20 0.52
ESR2 Q92731 1/20 0.52
KDM4E B2RXH2 3/20 0.50
CYP19A1 P11511 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
SLC16A3 O15427 1/20 0.50
TTR P02766 1/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4409944 0.90 F2RL1 (0.56) IAPPTRPV1ESR1ESR2KDM4E
SCHEMBL22414097 0.88 ESR1 (0.55) IAPPTRPV1ESR1ESR2KDM4E
SCHEMBL8108885 0.87 ESR1 (0.62) IAPPTRPV1ESR1ESR2KDM4E
SCHEMBL1053043 0.86 IAPP (0.66) IAPPTRPV1ESR1ESR2KDM4E
SCHEMBL13267781 0.85 IAPP (0.61) IAPPTRPV1ALDH1A1LMNATDP1
SCHEMBL105765 0.83 TDP1 (0.62) IAPPALDH1A1CYP1A2SLC5A1SLC5A2
Letestuianin C SCHEMBL4410123 0.83 F2RL1 (0.60) TRPV1ESR1ESR2KDM4ECYP19A1
SCHEMBL27921443 0.82 IAPP (0.68) IAPPTRPV1ESR1ESR2KDM4E
SCHEMBL27639928 0.82 ACHE (0.53) IAPPTRPV1ESR1KDM4EALDH1A1
SCHEMBL24242163 0.82 IAPP (0.58) IAPPTRPV1ALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024880-B High-temperature-resistant plastic-wood material composition and plastic-wood product 美新科技股份有限公司 2024-05-24 CN claimed
CN-117024880-A High-temperature-resistant plastic-wood material composition and plastic-wood product 美新科技股份有限公司 2023-11-10 CN claimed
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
EP-0374184-B1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE MEDICINE (US) 1994-01-12 EP claimed
US-5216024-A Compounds such as methyl p-hydroxypenyllactate, derivatives BAYLOR COLLEGE OF MEDICINE (US) 1993-06-01 US claimed
WO-1993001824-A1 COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS BAYLOR COLLEGE OF MEDICINE (US) 1993-02-04 WO claimed
EP-0374184-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES. BAYLOR COLLEGE MEDICINE (US) 1990-06-27 EP claimed
WO-1989000849-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1989-02-09 WO claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20250011293-A1 LEUKOTRIENE SYNTHESIS INHIBITORS NAEGIS PHARMACEUTICALS INC. (CA) 2025-01-09 US disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
WO-1993001824-A1 COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS BAYLOR COLLEGE OF MEDICINE (US) 1993-02-04 WO disclosed
WO-1991017749-A1 GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1991-11-28 WO disclosed
EP-0374184-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES. BAYLOR COLLEGE MEDICINE (US) 1990-06-27 EP disclosed
WO-1989000849-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1989-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA IAPP 2522/4885TRPV1 3969/4885ESR1 3581/4885
US-20250011293-A1 LEUKOTRIENE SYNTHESIS INHIBITORS LTC4S, LTB4R2, LTA4H IAPP 2392/4885TRPV1 428/4885ESR1 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.