Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079132 | 1.00 | TLR8 (0.40) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11079027 | 0.90 | TLR8 (0.41) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11077225 | 0.90 | LMNA (0.50) | EPHX2GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL11079005 | 0.90 | TLR8 (0.41) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11077229 | 0.90 | LMNA (0.50) | EPHX2GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL11068999 | 0.89 | POLB (0.38) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11068997 | 0.89 | POLB (0.38) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11071573 | 0.89 | PTGS2 (0.44) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11071570 | 0.89 | PTGS2 (0.44) | TLR8TLR7EPHX2GAANPSR1 | |
| SCHEMBL11079418 | 0.89 | EPHX2 (0.50) | EPHX2GAANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |