Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11078533 | 0.80 | OPRL1 (0.55) | OPRM1OPRL1 | |
| Morpholine SCHEMBL11079848 | 0.78 | OPRM1 (0.41) | OPRM1 | |
| Morpholine SCHEMBL11068267 | 0.77 | OPRM1 (0.47) | OPRM1OPRL1 | |
| SCHEMBL11074085 | 0.76 | ALOX5 (0.56) | ALOX5OPRM1OPRL1MAOBKDM1A | |
| SCHEMBL9136360 | 0.74 | ALOX5 (0.60) | ALOX5MAOBALDH1A1 | |
| SCHEMBL22091686 | 0.74 | OPRL1 (0.58) | OPRM1OPRL1MAOB | |
| SCHEMBL11075823 | 0.73 | OPRM1 (0.49) | ALOX5OPRM1OPRL1MAOBKDM1A | |
| SCHEMBL11075825 | 0.73 | OPRM1 (0.51) | OPRM1OPRL1MAOBKDM1A | |
| Morpholine SCHEMBL11071701 | 0.72 | OPRL1 (0.38) | OPRM1OPRL1MAOBALDH1A1 | |
| SCHEMBL9217663 | 0.72 | ALOX5 (0.61) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |