Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11073425 | 0.87 | SLC6A4 (0.39) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11068267 | 0.85 | OPRM1 (0.47) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11643273 | 0.85 | OPRM1 (0.45) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11077287 | 0.85 | OPRM1 (0.44) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11078533 | 0.83 | OPRL1 (0.55) | OPRM1OPRK1 | |
| SCHEMBL22798751 | 0.83 | OPRM1 (0.44) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11642438 | 0.83 | OPRM1 (0.42) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Hydrochloric Acid SCHEMBL20917497 | 0.82 | OPRM1 (0.43) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11069454 | 0.79 | DRD2 (0.36) | OPRM1SLC6A4SLC6A2OPRD1MEN1 | |
| Morpholine SCHEMBL11077264 | 0.78 | ALOX5 (0.45) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |